You're not going to get a more central hotel than this, just steps from the main square and with views of the Çifte Minare Medrese's minarets from some rooms. The Buruciye is excellent value with comfortable, classically styled rooms, home to mod-con home comforts (big flat-screen TVs, kettles, spacious showers), plus the added bonus of friendly, helpful staff.
If they're not busy they'll often bump you up to one of the corner suites with little sitting areas and even more space to spread out.