This stylish gourmet deli and wine shop has been pouring the good stuff since 1938, when it was started by grandmother of current host Cesare, who will expertly guide you through his daily selections of wine by the glass (from €3). Of Cesare's 120 wines or so, half are from Orvieto.
There are also generous salumi and cheese taglieri (tasting platters; €8 to €18) and craft beers from Birra Perugia and Birra Flea, for those not feeling the grapes. Take a seat outside on Via del Duomo or assemble an epic picnic (cheeses, pâté, olive oils, fresh truffles) and take a bottle to go.