Steeped in history, the Residenze Gregoriane offers a night to remember. Its four suites, all decorated in classic antique style, occupy the 16th-century Palazzo Mancini-Torlonia. Frescoes adorn the historic building, many by the same artists who worked on Villa d'Este, and there's a magnificent internal courtyard adorned with ceramic tiles and seashell mosaics.
Room rates also cover use of a spa and dipping pool in a vaulted cellar that was formerly used as a paper mill.