Anyone remotely hip ultimately gravitates to this Old Town bar with a pharmaceutical theme. Occupying a gorgeous colonial building, the bar is spread over three floors: the ground floor is a sleek, low-lit lounge perfect for an aperitif, while upstairs there's a kitchen and pool table. One more floor up is the always-packed roof-terrace bar, serving imaginative aguardiente cocktails.
The entire space is easily one of Cartagena's most sophisticated options and the roof terrace is perfect for tropical nights.