The 'Signature' in the name means this well-located shop – just off Robson St at Bute – is one of the larger-format BC government liquor stores. You'll find a big selection of pretty much anything you might want to imbibe, including a back wall of regional and international beers, and a large array of wines from around the world.
If you're a beer fan, make sure you peruse the BC craft beer selection. Many are available in (larger) single bottles, so you can sample a few without committing to a six-pack.