Housed in a charming 1920s-era villa, Issaya is a top-of-the-line outpost serving Thai food. Dishes alternate between somewhat saucy, meaty items and lighter dishes using produce from the restaurant’s organic garden. Sample the soft shell crab in egg sauce or the creamy and spicy lamb massaman curry, and you'll know why it's regarded as one of Bangkok's best Thai eateries.
The restaurant can be a bit tricky to find, and is best approached in a taxi via Soi Ngam Du Phli.