Set in an 1873 convent, this American-run B&B features plush lodgings amid family heirlooms and period furniture. The setting is serene, with a wraparound balcony overlooking the action of Casco Viejo. Watch for the friendly ghost rumored to dwell on the entrance staircase. There's also a downstairs cafe with great coffee, run by California natives Alyce and Rich.
Casa Sucre
Panama City