The 96-room Opus kick-started Vancouver's boutique-hotel scene and, with regular revamps, it's remained one of the city's top sleepover options. The designer rooms have contemporary-chic interiors with bold colors, mod furnishings and feng-shui bed placements, while many of the luxe bathrooms have clear windows overlooking the streets (visiting exhibitionists take note).
A model of excellent service, the Opus has a slick on-site bar and a quality Italian restaurant, while all rooms come with loaner iPads. And if you need to get around town, you can borrow a gratis bike – an excellent incentive not to bring your car since parking here costs $45 per night.